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11,16 If your family has a history of neural-tube defects, recurrent miscarriage, or elevated homocysteine, or if you have been tested and carry an MTHFR variant, methylfolate is generally preferred

In the SURPASS-2 study conducted on T2DM, when comparing the effects of tirzepatide to a selective GLP-1R agonist, serum triglyceride and apolipoprotein C-III levels were significantly more reduced by tirzepatide than by both dulaglutide and placebo [18]